 In the GI system we have over a thousand different bacterial species which plays an essential role in food metabolism, nutrition and drug uptake. There is interest in terms of studying how this microbial community affects different kind of diseases such as obesity, diabetes and also metabolic syndromes. There is a limited understanding because of the limited access that we currently have at different locations throughout the GI tract. This is the first time that we've developed a low-cost sampling device that will allow targeted sampling throughout the GI tract. So the capsule is composed of a 3D printed container that holds a super absorbent hydrogel. Upon entering the GI tract, the pH sensitive polymer on top of the capsule will dissolve. The fluid inside the targeted location will enter the capsule. The hydrogel will swell, it will basically absorb and collect the targeted microbial community. With its swelling, it will push a plunger that will close the capsule until the capsule is extruded from the body. So once the capsule is extruded, because of the 3D printed geometry that we have, it could be easily unscrewed and the sampled material could be extracted from the capsule. So we envisioned that this technology could further advance our understanding of how this microbial community affects these different diseases. Because of the simplicity of the design and its low cost, it could be easily used in different terms of clinical settings and also help improve our understanding about how to develop better drugs that could address these issues and how could we design therapeutics that better could alter or be more compliant with the microbial community.