 So, I'm Shrek Zhang, assistant professor at the Habermas School and associate bioengineer at the Brigham Room Hospital. Our lab has been really working on bio-fabrication perspectives, primarily bio-printing and organ-trip devices, to allow fabrication of human tissues and organs for different applications. Yeah, bio-fabrication basically means the use of cells and possibly associated biomaterials to allow generation of functional tissues and organ type systems to allow emulation of the human counterparts for their functions and downstream applications. Yeah, so as mentioned, I mean bio-fabrication can be potentially applied to different aspects. So, one thing is 3D fabrication of these human tissues and organs and if you then apply those towards, for example, let's say different donor, patient derived geometries of the tissues or cell types in there, then you can start to really personalize these medicines according to different patient needs. So, that's one aspect but also another aspect mentioned is these organ-trip devices, basically in vitro models of human tissues and organs where you can also imagine you can combine them with cells that are coming from different patients, different donors, different people populations and then allow them to really promote our capacity to screen drugs in a better way. So, those are perspectives I think might be relevant to procedure medicine with bio-fabrication. Yeah, sure, definitely. So, in our own lab we have been really interested or heavily focused on vascular bio-printing, for example. So, vasculature is essentially one of the most important components of human system because every single tissue essentially has the vasculature in there in both cases. So, we have been really focusing on using bio-printing or on-trip devices to emulate human vasculature and then with that you can, for example, combine that towards a cancer model like things like that to then apply precision medicine concepts in there for these different scenarios. Yeah, that's a good question. So, I would say it's probably anywhere between 5-10 years to decades. I mean, depending on the complex of the organ, certain organs are a little less complex. So, likely you can have some of those organs already fabricated within the next decade or so but then for some internal organs that are super complex then might be needing a little longer time. Sure, yeah. So, I think eventually, well, we have been working primarily on the bio-fabrication or fabrications of the things. So, eventually I think comes back to a biological problem. So, eventually whatever you're trying to fabricate has to be functionally relevant to the biology itself. So, I think that's really where more efforts have to be placed on to allow generation of truly functional and biologically relevant tissues and organs for these purposes. Yeah, definitely. So, I think that's a very unique and interesting setting because there's mutual need. For example, as engineers, right, so we develop technologies all the time and then we have to apply them to something at the end. So, then that's where, for example, clinicians and all the doctors are coming in, where they have problems, right? And oftentimes if they have, well, if they're in hospital without engineers, they have a problem but they can't solve them. But now if you have both engineers and the clinicians together in the same environment then it's actually very beneficial of both ways. I mean engineers can actually go to the doctors and then really apply the technologies to the actual final use. But then on the other side the doctors or clinicians can come over when they have a question so we can actually start to really, I mean, work together in different ways to really push the technologies into the actual kind of translation at the end. Yeah, so I think that's a good question. I mean it's a very nice city here and I mean people are very warm, welcoming and again I think being able to have a conference like this or something like this that's really multi-disciplinary as we discussed. That's very helpful because I mean again you have people from different disciplines and then they convene and communicate and exchange ideas and I think really from there it's going to be prompting different new areas coming through and also maturation of existing areas so a lot of new collaboration is potentially happening over there as well and also the education of the newer generations for them to be coming to this important area in the future.