 Ladies and gentlemen, to present the Leslie Garry Brenner Award for Innovation in Science, we introduce to you Hereditary Disease Foundation, member of the Board of Directors, and founding trustee Frank Garry. So I joined this outfit 50 years ago when it was starting because there was a guy named Milton Wexler, he was my shrink actually, who taught me about anger management. And I wouldn't be here today if he hadn't taught me about that. During the early days of this operation, we were looking into, because he and I knew a bunch of artists, and we, I'm being an artist and working that way. We had meetings with young scientists and talked about creativity and how that happens and exploring the unknown and the idea that you don't do something, if you know what you're going to do in advance, you don't bother to do it. I attended many of those group meetings, the early meetings, I don't know how many of you were there, but they had a group of 16 maybe young postdocs sitting around a table, and then they had a senior scientist ring, and they weren't allowed to talk unless they were asked a question. And that was a fantastic thing to behold. I used to go, I didn't understand what they were talking about. I still don't know what the COD8 nucleus is, even though they talked about it a lot. I'm sure it's back here somewhere. But the idea that there is such a similarity between the search in science and the search as an artist and the very close relationship to those efforts and the similarities are great. So I learned a lot about it, spent a lot of time with it, and I'm honored to still be part of it. A few years ago, my young daughter passed away, not from Huntington's, from Ovarian Cancer, but she was in the hospital and she had some, she owned up some property and stuff, and she asked me if I would be sure that was donated for science for the Hereditary Disease Foundation, and I decided to match it. So we created a fund in her name, Leslie Gary Brenner, I forget which sequence we did, Leslie Gary Brenner, I did it right, in her name, and we give that award every year. And the idea was to give it without any strings, thinking, I was thinking about young scientists, you give them 100k with no strings and see what happens, and I love that idea, the freedom that that implied, and I think that's the idea to continue until we met the current honoree, Frank Bennett. And I'm honored tonight to be the one to bestow the award on him, and I think he gave the money back, I shouldn't have said that, I just free him to you. Anyway, Frank Bennett, please come forward. Thank you very much, Mr. Gary, it's a real pleasure to meet you, and I'm sorry I never had the opportunity to meet your daughter, she sounds like a wonderful human being. And there's a lot of people I'd like to think, but I won't have time, but I did want to acknowledge that developing drugs really is not a single person endeavor, if anything in medicine is a team sport, developing drugs is a team sport, and there are a lot of people who contributed to this effort. Some of the people in this room were instrumental in identifying the gene and understanding the biology of the gene, which is still very important today to a lot more work to be done. And I really do thank the people in the room for everything they've done to make this possible. And then I'd also like to thank my collaborators who worked with me on this project, in particular Don Cleveland at UCSD, and his very talented post-doctoral fellow, Holly Kordesavich, who now works at IONUS because she was so talented and continues to work on this project. We're really key for doing some of the initial studies of mice, and then a number of our collaborators at IONUS and colleagues, as well as at Roche, who helped move an idea into the clinical trials were really key. And finally, the clinical investigators, including last year's awardee, Sarah Tabrizzi, who really led the clinical development for the phase one trial, should be acknowledged as part of that. And then finally, I wouldn't be here today if it wasn't for my wife, Paula, and my three sons that have really put up with me for the last large number of years. And have encouraged me to pursue my dreams in science and working on therapies to help people that have a need. And so thank you very much. And finally, I could think of no better use of the money. I worked for a pharmaceutical company, and so I didn't feel like it was appropriate to put it in the coffers and get lost there. So I felt the best use of the money is really to provide it back to the foundation and continue this great work that Nancy and the team are doing. So thank you.