 Neutrostaticals are a type of food or dietary supplement that contains additional health benefits beyond its nutritional value. They are often marketed for the prevention and treatment of certain conditions. Natural ingredients such as vitamins, minerals, herbs, and other botanicals are commonly found in these products. However, many of these ingredients are sensitive to stomach acids and may cause nausea or vomiting when taken orally. To address this issue, manufacturers have developed gastro-resistant coatings made from enteric polymers, which are not considered natural ingredients and are not approved by regulatory agencies. These coatings are designed to protect the ingredients from being broken down by stomach acids until they reach the small intestine where they can be absorbed. Unfortunately, these coatings are not always effective and can lead to poor product performance. This paper reviews the use of natural materials in developing gastro-resistant products, their limitations, and potential applications. The authors also identify areas of research that could help improve the effectiveness of these products. This article was authored by Shua Barbosa, Barbara Conway, and Hamid Machint. We are article.tv, links in the description below.