 The study shows that burn injury leads to activation of the endoplasmic reticulum, ER, stress response, which results in increased expression of X-box binding protein 1, XBP1s, messenger ribonucleic acid, mRNA, down-regulation of gluconeogenic enzyme glucose, 6-phosphatase, G6-pase, and sustained glucose tolerance in the post-burn ep phase. This article was authored by Natasha Seabrooks, Alexandra H. Marshall, NQA80, and others.