 The Comprehensive Post-Acute Stroke Services, Compass, study is one of the first large pragmatic randomized controlled clinical trials using comparative effectiveness research methods, funded by the Patient-Centered Outcomes Research Institute. In the Compass study, we compare the effectiveness of a patient-centered, transitional care intervention versus usual care for stroke patients discharged home from acute care. Outcomes included stroke patient post-discharge functional status and caregiver strain 90 days after discharge and hospital readmissions. A central tenet of Patient-Centered Outcomes Research Institute-funded research is stakeholder engagement throughout the research process. However, evidence on how to successfully implement a pragmatic trial that changes systems of care in combination with robust, stakeholder engagement is limited. This combination is not without challenges. To maximize stakeholder engagement throughout the Compass study, we employed a conceptual model with the following components. 1. Patient and other stakeholder identification and selection. 2. Patient and other stakeholder involvement across the spectrum of. This article was authored by Sabina B. Giesel, Karen Potvin Klein, Jacqueline Halliday, and others. We are article.tv, links in the description below.