 This systematic review synthesizes current evidence on the role of smartphone-based audiometry in diagnosing hearing loss and identifies factors that influence its diagnostic accuracy. The results show that smartphone-based audiometry has high sensitivity, specificity and accuracy in diagnosing hearing loss with an area under the receiver operating characteristic curve of 0.96. Factors such as patient age, equipment used and soundproof boots were found to significantly affect diagnostic accuracy. Overall, smartphone-based audiometry may serve as a reliable and accessible approach to hearing evaluations in settings where conventional PDA is unavailable. This article was authored by Qi Hao Chen, Heng Yu-Hailey Lin, Mao Che-Wang and others.