 If there is one thing that we all are terrified of is probably the thought of how we might die. Is it going to be a car crash, perhaps an aggressive cancer or a deadly virus? But according to the World Health Organization, heart disease beats them all. Heart disease has been the leading cause of death for the past 15 years. It kills an Aussie every 12 minutes, hopefully not in the next 3 minutes. But if you are the unlucky one, it doesn't matter whether we are in a hospital, the chances that you would make it through is slim. Now people have been trying to find ways to treat heart disease for centuries without much success. But I have discovered something very unusual that can help and it has to do with how your heart beats. You see, our heart is made up of millions of cells like these that can contract and relax causing the heart to beat. But how does it do it? How does it beat? The key is calcium. When calcium enters the cells, the cells contract. And when calcium is removed, cells relax. If calcium is not removed in time, it will kill your cell. So what removes calcium so efficiently keeping your heart alive and pumping? A protein called CERCA does this job for you. Majority of the heart complication happens when CERCA gets a bit lazy. And if CERCA decides to pack its bag and take a vacation, you're doomed. You can rest in peace. So when scientists took mice with heart disease and treated them with CERCA, they go better. But when we tried the same thing in humans, we failed. What did we do wrong? Is it because we forgot to keep the humans in cages? Obviously not. Now, CERCA moves dramatically changing its structure to remove calcium. To understand this better, I started growing beating heart cells on a plate. By exposing these beautiful beating cells to ultraviolet rays, I can capture biomolecules that interact closely within the cell. Using this method, I discovered that CERCA interacts with another biomolecule called an RNA. And we believe that this RNA could either stop CERCA or help CERCA in removing the calcium from the cell. This unusual relationship between CERCA and RNA, if exploited, could potentially treat heart disease. And maybe, and maybe then, we do not have to lose someone every 12 minutes. Thank you.