 The Bot Shell OPA Trans-Study was a unique collaboration between transgender women and researchers in South Africa. It was the first hip bio-behavioral survey conducted with transgender women in the country, and it used a community-based participatory research approach to ensure that the needs and concerns of the transgender community were taken into account. This included the establishment of a steering committee made up of transgender women who provided valuable input on the study design and implementation. Additionally, the study team worked closely with the transgender community to build trust and establish ownership of the survey, which helped to ensure that the survey addressed relevant issues. This article was authored by L. Lee and Vanda Mawa, or Anas Khloéit, Helen Sava, and others.