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Marek's disease in free-range chicken

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Uploaded on Oct 11, 2011

Marek's disease (MD). A chicken presenting difficult and stiff walk, mainly due to right leg weakness. The right leg weakness is due to an inflammatory reaction in the sciatic nerve, after its infiltration by tumoral T lymphocytes (from thymus), typical of classical Marek's disease (neurolymphomatosis). The diagnosis was confirmed by histopathology and the determination of Marek's disease virus (MDV) DNA [part of meq gene sequenced, aligned and grouped with serotype 1 MDV] in feather follicles and thymus. This form is not typical and the untrained clinician lacking of laboratory support would disconsider MD.

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