 Ferrolic acid, FA, a ubiquitous natural phenolic phytochemical present in seeds, leaves, both in its free form and covalently conjugated to the plant cell wall polysaccharides, glycoproteins, polyamines, lignin and hydroxy fatty acids. FA plays a vital role in providing the rigidity to the cell wall and formation of other important organic compounds like coniferal alcohol, vanolin, synaptic, dipherolic acid and curcumin. FA exhibits wide variety of biological activities such as antioxidant, anti-inflammatory, antimicrobial, anti-allergic, hepatoprotective, anticarcinogenic, antithrombotic, increased sperm viability, antiviral and vasodilatory actions, metal chelation, modulation of enzyme activity, activation of transcriptional factors, gene expression and signal transduction. This article was authored by Nareesh Kumar and Vikas Pruthi.