 This study developed a novel multifunctional hydrogel composed of iron, zirconium, polydopamine, and carboxy-methylchytosin. It was designed to combine the Fenton reaction, which produces hydroxyl radicals and photothermal conversion, which uses near-infrared light to heat up and destroy cancer cells. This combination of reactions could potentially be used to treat tumors more effectively than either reaction alone. The hydrogel was tested in vitro and in vivo, and it showed promise as a potential tool for treating tumors. This article was authored by Xiaoyi Zheng, Hengwu, Shige Wang, and others.