DNA Replication Cartoon





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Published on Jan 7, 2009

Our second cartoon made for our AP Biology class. Comments would be appreciated!

We realize that some of this is hard to understand, so here is the script of the second half:

"Helicases travel to the origin of replication to unwind the DNA, forming a replication fork.

Single strand binding proteins hold the two template strands apart.

On the leading strand, the enzyme primase attaches to the DNA to synthesize and add an RNA primer.

Next, DNA polymerase III adds DNA nucleotides to the RNA primer, but only in the 5 prime to 3 prime direction.

On the leading strand, nucleotides can be added continuously. The process is different for the lagging strand.

First on the lagging strand, primase removes the single strand binding proteins. Then, it forms an RNA primer.

DNA polymerase III adds nucleotides to the 3 prime end of the RNA primer.

These short segments are called okazaki fragments.

As a finishing touch, an enzyme called DNA ligase bonds the okazaki fragments together. This completes the lagging strand."

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