 This study found that individuals with hydratonitis separativa, Hs, had a worse metabolic profile than those without Hs, regardless of their body mass index, BMI. Individuals with Hs were more likely to have higher levels of visceral fat, higher blood pressure, and higher markers of insulin resistance compared to those without Hs. Additionally, individuals with Hs were more likely to be categorized as having metabolic syndrome, even if they were of normal weight. Furthermore, individuals with Hs who were also classified as metabolically unhealthy were at greater risk of developing Hs. These findings suggest that individuals with Hs should be screened for metabolic disorders and given appropriate treatment to reduce their risk of developing cardiometabolic diseases. This article was authored by Dylan Mintoff, Rachel Agius, Stephen Fava, and others.