 One, background, a growing number of studies have shown that thiazolidindians, TZD, can be anti-soriatic. Chiodlitazone is a representative of the class of anti-diabetic drugs known as TZD. TZD can activate nuclear peroxis and proliferate activated receptors, PPAR, see, PPARs are expressed on epidermal keratinocytes and exert their effects by promoting the terminal differentiation of keratinocytes inhibiting epidermal. This article was authored by Guaixin Chang, Jin Wang, Jingxin Song, and others.