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Uploaded on Sep 29, 2011
Air date: Wednesday, September 28, 2011, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local Category: Wednesday Afternoon Lectures Description: Recent developments in biomaterials technology have enabled the production of biodegradable, cytocompatible tissue engineering scaffolds that can be tailored with appropriate mechanical and biological signals to restore damaged tissue in specific sites in the body. For example, our laboratory has developed a variety of biodegradable polymers for the controlled delivery of biologically active agents and/or progenitor stem cell populations to promote regeneration of tissues such as bone and cartilage.
Further, we have explored the application of bioreactor culture of progenitor cell populations to produce extracellular matrix constructs containing biologically active signals to direct cellular differentiation and tissue formation. Ongoing research in collaboration with clinical colleagues also involves the development of materials-based approaches for application in strategies for bone regeneration, with a vision for rapid clinical translation. This talk will present examples of biomaterials from our laboratory to illustrate recent advances in tailored biomaterials-based approaches for bone and cartilage tissue engineering.
The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.