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Published on Oct 21, 2016
Hormesis is the term that describes any process in a cell or organism that exhibits a biphasic response to exposure to increasing amounts of a substance or condition. Within the hormetic zone there is generally a favorable biological responses to low exposures to toxins and other stressors. A pollutant or toxin showing hormesis thus has the opposite effect in small doses as in large doses. Hormetics is the term proposed for the study and science of hormesis. A related concept is Mithridatism, which refers to the willful exposure to toxins in an attempt to develop immunity against them.
In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response. Such environmental factors that would seem to produce positive responses have also been termed "eustress". Dr. Walt Kozumbo and Dr. Ed Calabrese
Friday Informal Seminar Hour (FISH) Bridgewater State University Bartlett College of Science and Mathematics