 Current research suggests that early titration of oxygen in the out-of-hospital phase is not associated with improved survival and should therefore be avoided. Noradrenaline is the preferred agent over adrenaline when reducing the oxygen fraction after resuscitation. Higher blood pressures are not associated with better neurological outcomes, but prognostication bundles should be used. Newer biomarkers and techniques may help improve prognosis prediction in the future. This article was authored by Stefan Katzenschlager, Eric Pop, Jan Nent and others.