 This systematic review aimed to collect evidence on the effect of a digital care platform on quality of care parameters such as information availability, self-efficacy, continuity of care, and patient and health care provider reported experiences in oncological patients. The results showed that usage of a digital care platform enhanced information availability and self-efficacy, but there were no data available on its effect on continuity of care. Patient reported experiences were positive, while most barriers for implementation were identified at the professional level, such as increased workload and unattended release of medical information to patients. Most facilitators were found at the patient and innovation levels, such as improved patient-doctor communication and patient empowerment. The study highlights the need for further investigation of the effectiveness of digital care platforms, especially from high-quality studies, to address barriers and facilitate their implementation at the economic and political levels. This article was authored by Janna S. Hopps-Tacon, Lynn Verwage, C's J.H.M. VanLarhoven, and others. We are article.tv, links in the description below.