 Kamegatiella fafii, Pichia pastoris, is a yeast species that can be used to produce recombinant proteins from crude glycerol, a byproduct of the biodiesel industry. It has the ability to use crude glycerol as a carbon source, making it ideal for the transition towards a circular bioeconomy. Additionally, the use of Pichia pastoris can help reduce waste and create new opportunities for the production of high-value products. This article was authored by Nuria Bernat Camps, Nuria Bernat Camps, Katerina Ebner, and others.