Uploaded on Oct 10, 2010
http://www.sponauglewellness.com | Brain chemistry expert Dr Rick Sponaugle explains that kids and adults who inherit the DRD2 dopamine receptor gene can become suicidal when prescribed a serotonergic antidepressant. WHY? Do the drugs doctors prescribe to relieve depression make some young people more likely to attempt suicide? And if so, why? | http://www.youtube.com/watch?v=VkdaxP
"I told my mom I just wasn't happy, and of course being a mom you try to fix it but she just couldn't."
Two young people both suffered symptoms of depression. Both turned to anti-depressants for relief. For one, the controversial drugs seem to be working.
For the other, antidepressants brought on thoughts of suicide.
Rebecca remembers, "My mom saw me in the kitchen with a knife and she stopped it."
Some doctors say chemicals in the brain, including serotonin and dopamine, control everything from wakefulness to moodiness, joy to despair. When those chemicals get too
And doctors commonly prescribe drugs like Lexapro or Paxil that increase and restore the balance of serotonin in the brain.
Dr. Sponaugle explains, "Serotonin enhancing drugs work fine in teens who need a serotonin boost, however, serotonin enhancing drugs worsen a depression, and often cause suicidality, in those patients who suffer from a dopamine deficiency or a genetic deficiency of dopamine receptors in the nucleus accumbens. reward center."
Dr. Sponaugle says, "There is an inverse relationship between serotonin and dopamine in the brain synapse, the more serotonin in the synaptic cleft, the more inhibition of dopamine release from brain cell storage units. Subnormal dopamine activity in the pleasure or reward center typically goes undiagnosed by most psychiatrists who remain too focused on serotonin deficiency as the primary cause of depression."
Rebecca says, "It's just like, there's no reason to be here. That's the way you feel."
Instead of prescribing drugs like Lexapro or Paxil to patients like Rebecca who have inherited the DRD2 gene, Dr. Sponaugle says these patients need, "a good dopamine stimululant like Vyvanse with concomitant neutraceutical treament to naturally raise dopamine levels.
Dr. Helene Hubbard, board certified in behavioral pediatrics, agrees with Dr. Sponaugle.
Lynn is Kyle's mother. "A lot of it is educating. Parents need to be educated."
She says antidepressants are helping her son. He does take an ADHD stimulant as well. Her son says, "It's been so much better. I'm enjoying music more. I'm having fun. I have friends."
She said the long journey to get his medication right changed not only his mood but his music. "You have to have that willingness to ride that roller-coaster and know that it's not going to be perfect the first time."
So what do you do if you think your son or daughter is depressed and may need antidepressants? Both doctors say you need to find a medical professional well versed in brain chemistry and anti-depressants. And you have to be able to monitor your child closely during the weeks it takes for the medications to take effect.
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