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Published on Feb 7, 2011
Systemic lupus is associated with significant increases in premature heart attacks. Dr. Mariana Kaplan and her team at the University of Michigan Health Systems in Ann Arbor studied the abnormal function of stem cells that repair damaged blood vessels, an important factor implicated in heart disease in lupus. This study investigated the potential mechanisms by which abnormal vascular repair occurs in lupus and could contribute to designing treatments aimed at decreasing the risk of this potentially fatal complication.
In this video, recorded during the 2010 American College of Rheumatology Annual Scientific Meeting in Atlanta, Georgia, Dr. Kaplan explains some of her findings, possible implications for the data she developed from the LFA funded study, and the next steps in this research.