 In this study, three male patients presented with proton area and pathological changes suggestive of Fabry disease. Clinical and laboratory tests were conducted to rule out other potential causes for the symptoms. Electron microscopy revealed numerous membrane-bound inclusion bodies in podocytes, which were confirmed by biochemical testing to be absent of Fabry disease. Further investigation showed that the patients had taken certain medicines, including pitivastidine calcium, chlorithromycin, loxoprofen, and oprodysalone, which may have caused the inclusion bodies. This suggests that caution must be exercised when treating patients with such medications as they could potentially cause similar side effects. This article was authored by Atoshi Sakuraba, Takahiro Tsukamura, Tashi Tanaka, and others.