 This paper highlights the importance of advancements in biofabrication technology for treating soft tissue defects, specifically vascular tissues, through tissue engineered blood vessels as alternatives to blood vessel transplantation due to donor scarcity and patient conditions. The paper provides an update on current status of tissue reconstruction using autologous stem cells, scaffolds, and scaffold-free cellular transplantable constructs, with a focus on historical view of cardiovascular tissue engineering and stem cell biology, featuring studies from the last decade to trace trends and evolution of techniques for blood vessel tissue engineering. This article was authored by Judy Grace Nemono-Guanzon, Sir Jung Lee, Johann Robert Berg and others.