 Portulicaria afra is a medicinal plant traditionally used by African healers to treat skin conditions and dehydration. This study validated the use of pee, afra by testing its phytochemical presence, antioxidant activity, and antibacterial properties. The results indicated that pee. Afra had a high phytochemical presence in the methanolic extracts, with 7 out of the 10 phytochemical groups present. Additionally, the methanolic root extract exhibited the strongest DPPH scavenging activity, while the hexane leaf extract was the only one to exceed the acceptable upper limit. Furthermore, the methanolic and hot water stem extracts displayed the greatest zone of inhibition against tea. Coli, while the cold water and room temperature water extracts did not show any zone of inhibition against either bacterial strain. In conclusion, pee, afra has the potential to be used as a nutritional supplement due to its antioxidant properties, while its antibacterial properties could provide relief for me. Coli infections. This article was authored by Dominic Courtney Bosson, the B. Socat Legotefo, and Ida Mossana-Ryzenaw. We are article.tv, links in the description below.