 This study found that lymphadenectomy is beneficial for intrahepatic cholangiocarcinoma, ICC, patients with hyalurlesions, but not those with peripheral lesions. For patients with hyalurlesions, lymphadenectomy up to level 2, post-pancreatic or common hepatic artery nodes, can provide better outcomes than no lymphadenectomy. For patients with peripheral lesions, lymphadenectomy up to level 1, hepatoduodenal ligament node, may be sufficient. This article was authored by Yuzo Yumida, Kozi Itikagi, Tatsuomatsuda, and others.