 This study found that the practice of active management of the third stage of labor in Ethiopia was low. It also showed that educational status, taking obstetric care training, knowledge of AMTSL, and work experience of obstetric care providers were associated with the practices of active management of the third stage of labor. Therefore, obstetric care professionals should improve their academic level, knowledge, and skills in order to provide useful service to AMTSL and save mothers' lives. All obstetric care providers should get obstetric care training. Furthermore, the government should increase obstetric care professionals' educational level. This article was authored by Gedefe Nibret Mairiti, Alamu Degueyal, Tuchu Mushliya, and others.