 Good evening again everyone. This time it's for myself. I feel really honoured because this is a very special award Professor James Lance Award So I'm a neurology fellow at Alfred Hospital in Melbourne and also a research master's students with Monarch University My research project focused on the association between chronic migraine and cervical dystonia Migraines are leading cause of neurological disability in Australia with significant Destructions to work and social engagement Producing an estimated annual economic cost at 35.7 billion dollars neck pain with muscle tension is a frequent frequent complaint in migraine often associated with significant symptom related disabilities however Mechanism of this phenomenon is poorly understood and targeted treatment is lacking Our study aims to determine whether there's a link between chronic migraine neck with neck muscle spasm and cervical dystonia cervical dystonia is a real neurologic condition, but debilitating featured by involuntary neck muscle contractions leading to abnormal head postures Coexisting migraine and cervical dystonia has been observed and then reported clinically Which however only explained minority cases migraine with neck pain the majority of cases the nature the nature of Overly active neck muscles in the majority of cases migraine remains unclear So our project is the first study using MRI to investigate activated neck muscles in migraine and cervical dystonia several earlier studies have shown that exercise can induce muscle signal changes on a mar Sequence named T2 relaxation times Which therefore can distinguish active activated muscles from resting muscles? In the upcoming study we'll look at muscle signal changes in patients with migraine and Cycle dystonia and compare those changes to normal individuals Knowledge gained from this project will potentially improve understanding the nature and mechanism of neck pain in migraine and justify consideration of new treatment options For example, botulinum toxin injection into the activated neck muscles In addition to that I might provide a novel non-invasive tool to allow more precise target and identification for toxin injections for cytoic dystonia Last but not the least I don't want to repeat other winners everyone has expressed their thanks to the Brain Foundation I'm just want to say I just want to say I'm just as much grateful. Thank you