 This is a schematic diagram showing stomach. Stomach is divided into four parts anatomically. Part in continuation of esophagus is cardiac. The part projecting as a dome is known as fundus. Rest of the part of stomachs are divided into body. This part is body and the last 20 percent is anterum. Anterum continues as pyridorus. Entire stomach mucosa has glands which dip deep into the mucosa. Their opening into the mucosa is known as pit. But the glands in different parts have different cells and secretions. That is why they have different names also. Eighty percent of the mucosa till body has auxintic glands. Rest of the mucosa in anterum has pyloric glands. So let us see what is the difference between auxintic and pyloric glands. In this diagram we are seeing these glands. So the upper 80 percent has auxintic glands and rest of the 20 percent has pyloric glands. This diagram is showing that glands dip deep into the mucosa. So this is mucosa and both type of glands you see they are dipping into the mucosal layer and the opening is known as pit where they are opening into the lumen of the stomach. The pit continues as lumen of the gland. Now both types of glands at surface have surface epithelial cells. Then there are mucous neck cells. Surface epithelial cells and mucous neck cells secrete mucous into the lumen of the stomach. Apart from that surface epithelial cells also secrete bicarbonate into the lumen and these mucous neck cells also have another type of cells known as stem cells. Stem cells produce cells which can migrate both up and down along the glands to form other cells. But apart from these two types of cells which are present in both auxintic glands and pyloric glands, auxintic glands have varietal cells and chief cells also known as peptic cells. Parietal cells secrete HCl and intrinsic factor. Chief cells are the source of an enzyme pepsinogen which is converted into its active form pepsin by HCl. Auxintic glands also have intracromophen like cells which secrete histamine. As opposed to auxintic glands, pyloric glands have different cells at the base of the glands. These are G cells and D cells. G cells secrete gastrin while D cells secrete somatostatic. These different secretions from auxintic glands and pyloric glands have different functions. So it is important to know these cells and their secretions and we'll see later that how these secretions are important for regulation of secretion of hydrochloric acid.