 The Middle East has seen a rise in antimicrobial resistance due to overuse of antibiotics. To combat this problem, many countries have implemented national action plans, NAPS, which include surveying antibiotic use and implementing antimicrobial stewardship programs, ASPs. This study assessed antibiotic use in hospitals in the Middle East and compared it to published data from other regions. It found that antibiotic use was high, with Jordan having the highest rate at 98.1%. Additionally, postoperative antibiotic prescriptions were often used for extended periods of time to prevent surgical site infections. Based on these findings, the authors suggest a number of measures to reduce antibiotic use and combat AMR in the Middle East. This article was authored by Abdul Haseeb, Zikria Salim, Azil Fakmaqadmi, and others.