 The study examined the effects of different extraction methods on the antioxidant activity and bioactive compounds of lapidium myenii, maca. Maseration, maceration with shaking, ultrasonic assisted extraction, and reflux extraction were compared. Additionally, the effects of extraction time and solvents, water and ethanol, were evaluated. The results showed that water was a more effective solvent than ethanol for obtaining extracts with high antioxidant activity and phenolic content. However, some ethanol extractable valuable compounds specific for maca, such as macamides or fatty acid derivatives, were not present in water extracts. Furthermore, the study demonstrated that the extraction conditions can significantly affect the bioactivity of maca extracts. Therefore, when developing nutritional and therapeutic formulations based on maca extracts, it is important to consider the solvent used. This article was authored by Maghur Shadadzishyol, Agnieszka Rabouska, and Khatrajina Jandamilksarek. We are article.tv, links in the description below.