 So I am trying to develop gene therapy for patients with a skin disease called epidermal isospelosa or short EB. So EB is a relatively rare but very severe skin disease. And patients with EB have extremely fragile skin, which leads to blistering through the slightest touch or friction. So at the moment the therapeutic management mainly involves basic wound care, pain medication and there is no cure or permanent treatment option available for these patients. So these patients definitely have unmade medical needs and so we are trying to develop a permanent treatment option. So basically we are taking a small punched biopsy from a patient with EB and then we are able to isolate the skin cells and grow them in the lab. And then we will use CRISPR-Cas9 gene editing to correct the mutation that is causing the disease and revert it back to a healthy gene basically. And then we will grow skin in the lab using these corrected skin cells. So far there are only a handful of publications using CRISPR-Cas9 gene editing to treat these patients and no one has used the exact methods we are using in the lab.