 Human coronaviruses, HCOVs, are known respiratory pathogens associated with a range of respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome coronavirus, SARS-CoV, and MERS-CoV have thrust HCOVs into spotlight of the research community due to their high pathogenicity in humans. This article was authored by Yvon Zinny Lim, Yen Lingying, James Petam, and others.