 Gentamicin is a commonly used antibiotic that can cause kidney damage when administered in high dosages. Research has shown that antioxidants such as vitamin C and E can reduce the risk of gentamicin-induced kidney damage. In a recent study, Raphioncopii et al. found that erythropoietin, EPO, a hormone produced by the kidneys, could protect against gentamicin-induced kidney injury. The authors treated rats with gentamicin and then either left them untreated or supplemented them with EPO. After 10 days, they observed that the rats treated with EPO had lower levels of serum creatinine and blood urea nitrogen than those not given EPO. Histologically, the rats treated with EPO had less tubular necrosis compared to the control group. These findings suggest that EPO may have potential therapeutic applications in reducing the severity of gentamicin-induced kidney injury.