 So, when you try and bake from low to high poly, substance keeps crashing, not a problem. Now when this happened to me, a quick look at the official Adobe website helped me find a solution, so I'm gonna share it here with you guys. If things keep crashing, go to edit, settings, and under general, and baking options, uncheck enable live preview. That did it for me. But if you're still having problems, Adobe say you should try and also disable ray tracing. And that should solve most of your problems. Anyway, I hope that helps and as always, I hope you have a fantastic day and I'll see you around.