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REDUCE Chronic KIDNEY Disease Risk in TYPE 2 Diabetes Patients By FOLLOW This HEALTHY EATING TIPS

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Published on Sep 26, 2017

Reduced Chronic KIDNEY Disease Risk in TYPE 2 Diabetes! FOLLOW This HEALTHY DIET TIPS To Reduce KIDNEY PAIN, KIDNEY Stones & Eliminated Kidney Failure. Cardiovascular Complications of Diabetic Kidney Disease

Diabetic nephropathy is the most common cause of chronic kidney disease and represents a large and ominous public health problem. Patients with diabetic kidney disease have exceptionally high rates of cardiovascular morbidity and mortality. In fact, the excess mortality among patients with diabetes appears to be largely limited to the subgroup with kidney disease and explained by their high burden of cardiovascular disease. The mechanisms underlying the strong association between diabetic kidney disease and various forms of cardiovascular disease are poorly understood. Traditional risk factors for cardiovascular disease, although prevalent among those with diabetes, do not fully account for the heightened risk observed. Despite their susceptibility to cardiovascular disease, patients with chronic kidney disease are less likely to receive appropriate risk factor modification than the general population. Moreover, as patients with chronic kidney disease have commonly been excluded from major cardiovascular trials, the evidence for potential treatments remains limited. Currently, mainstays of treatment for diabetic kidney disease include blockade of the renin-angiotensin-aldosterone system, and control of hypertension, hyperglycemia and dyslipidemia. Increased awareness of the vulnerability of this patient population and more timely interventions are likely to improve outcomes, while large evidence gaps are filled with newer studies.

Keywords: coronary artery disease, diabetes mellitus, chronic kidney disease, end-stage renal disease

Patients with chronic kidney disease could be at risk of type 2 diabetes

New research shows that chronic kidney disease shares a link to the development of type 2 diabetes.

The findings were made by scientists at the University of Montreal Hospital Research Centre, who believe that, should their findings be confirmed in further studies, patients with chronic kidney disease might require antioxidants to protect against type 2 diabetes.

Chronic kidney disease occurs when patients suffer a loss of kidney function, and can no longer eliminate toxins from the blood. Patients have to either undergo kidney transplantation or dialysis to get rid of these toxins.

In new observations of mice and human samples of chronic kidney disease, Montreal researchers found that around half had elevated blood glucose levels.

When they investigated further, they also noted that the samples had impaired insulin secretion from pancreatic beta cells, which occurs in type 2 diabetes.

Type 2 diabetes is a known cause of chronic kidney disease, and lead researcher Dr Vincent Poitout insists that the opposite is also true.

"We identified molecular mechanisms that may be responsible for increased blood glucose levels in patients with non-diabetic chronic kidney disease. Our observations in mice and in human samples show that the disease can cause secondary diabetes," he said.

Poitout's team believe that when the kidneys fail, a waste product called urea builds up in the blood. This is normally filtered by the kidneys and excreted in urine, but not in patients with chronic kidney disease.

"In patients with chronic renal failure, the kidneys are no longer able to eliminate toxins. Urea is part of this cocktail of waste that accumulates in the blood.

"This study demonstrates that urea is directly responsible for impaired insulin secretion in chronic kidney disease," said Laetitia Koppe Koppe, who worked on the study.

The study team now plan to conduct further studies to validate these findings in humans, which could lead to new treatment approaches to protect beta cells in people with kidney disease.

The findings appear in the Journal of Clinical Investigation.

Can glipizide cause kidney damage?
Sitagliptin is as effective as glipizide at lowering blood sugar levels in patients with type 2 diabetes and chronic kidney disease. Sitagliptin is less likely than glipizide to cause dangerously low blood sugar levels. Patients on sitagliptin tend to lose weight, while those on glipizide gain weight.

Can dialysis cure diabetes?
No diet or treatment can reverse the damage done to the kidneys. The diabetic dialysis diet will keep you healthy by managing your blood glucose levels and lessening the chances of other complications resulting from diabetes and kidney disease.

How do you keep your kidneys healthy?
What can you do for your kidneys?
Keep fit and active. ...
Keep regular control of your blood sugar level. ...
Monitor your blood pressure. ...
Eat healthy and keep your weight in check. ...
Maintain a healthy fluid intake. ...
Do not smoke. ...
Do not take over-the-counter pills on a regular basis.

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