 Our group is really interested in how diabetes or diabetic patients can have such a high risk for heart disease and we want to know what are the mechanisms behind that. Diabetic patients have increased blood glucose which is what is commonly known and used to diagnose diabetic patients but actually they also have increased levels of fructose sugar in the blood and we think that it's that fructose sugar that might be getting into the heart and binding to different parts of the cell and actually changing the way that they function. Fructose is one half of the main sugar that we eat which is sucrose. So sucrose is one glucose, one fructose and so we're eating that all the time and all the sweet things that eat sweet foods we're exposed to fructose sugar. So it's not just about fruit, we do obtain it from fruit but we're getting really high levels from other things like chocolate bars and soft drinks. So we want to understand how fructose is getting into the heart and we've identified that there is actually a transporter in the cell which can bring that fructose in. So it is getting in there and then what is it going to do? Is it just used as another fuel like glucose or could it actually be stored away in the heart muscle cell and do damage in that way? We have some convincing evidence to say that fructose definitely gets in there and it does something but understanding exactly what's happening in the diabetic scenario is another story. So that's where we're really looking at more diabetic tissues and that kind of thing.