 A community-wide outbreak of measles due to AD4 genotype virus occurred in Madrid, Spain between February 2011 and August 2012, affecting mostly unvaccinated individuals, particularly those from the Roma community. Control measures included bringing forward the first vaccination dose for children, active recruitment of unvaccinated children, and reinforcing vaccinations for healthcare workers and the Roma population. High vaccination coverage with two doses of MMR vaccine is necessary for specific groups such as young adults, the Roma population, and healthcare workers. This article was authored by El Gossier Comas, M-audibus Gavin, J.C. Sons Morino, and others.