 One of the things that's really important for me this evening is to get people talking. I've got lots of opinions, I've got lots of viewpoints, I've thought about many of these topics for many years. I have an audience full of young scientists who are bound to have their own ideas from having watched things on TV, from their experience growing up in different countries, different cultures. What can I learn from them this evening in their discussion? That's going to be very important for me because very often I will say this is the way it is when you hear somebody else talking about it, well maybe not, maybe I have to come at that from a different angle. So that's the great hope for me this evening. Ask some tricky questions and then I can walk out of the room and let everybody else discuss it.