 Alkali treatment of natural fibers can improve the mechanical, chemical, and thermal characteristics of natural fiber-reinforced epoxy composites. The optimization of four key process parameters for alkali treatment of KenaF fiber using orthogonal array-oriented fractional factorial experimental design revealed that 6% NaOH solution, 30°C process temperature, 8 hours process time, and 115 fiber-to-solution weight ratio are identified as optimum process parameters for a tensile strength of 58.16 mPa. This article was authored by our Suthi Skumar, Nevedatha Malidharan, and Ravishankar Sothya Mathi.