 The abstract summarizes the research conducted on the structure of the CDK2, cyclin-ACKS1P27SKP1SKP2 complex. It explains how the structure of this complex was obtained through cryo-electron microscopy and how it supports previous analyses of the dynamics of PE27. Additionally, it discusses the importance of the flexibility of the complex in order to understand the regulation of PE27. This article was authored by Rihanna J. Rowland, Richard Heath, Daniel Maskell, and others.