Rgs16::GFP;KIC mouse (P42) with a PDA tumor in the head of the pancreas. Light sheet microscopy was used to capture planar images of the duodenum and pancreas head. A computer generated 3D rotational movie shows Rgs16::GFP expression in a PDA tumor, several small areas of neoplasia and normal acinar cells in lobes of the exocrine pancreas. Rgs16::GFP is expressed in presumed neuroendocrine cells within villi of the duodenum. The original research can be accessed at http://dmm.biologists.org/content/8/1...