 Biosensors are increasingly being used in drug discovery, biomedicine, food safety standards, defense, security, and environmental monitoring. The development of precise and powerful analytical tools using biological sensing elements such as glucose oxidase electrodes has led to the invention of biosensors. Glucometers utilizing the strategy of electrochemical detection of oxygen or hydrogen peroxide have been used to detect glucose levels. Recent advances in biological techniques and instrumentation involving fluorescence tagging to nanomaterials have increased the sensitive limit of biosensors. Aptimers, peptide arrays, and molecular imprinted polymers provide tools to develop innovative biosensors over classical methods. Integrated approaches provide a better perspective for developing specific and sensitive biosensors with high regenerative potentials. Different types of biosensors ranging from nanomaterials, polymers, and microbes have wide potential applications. It is important to integrate multifaceted approaches to design biosensors that have the potential for diverse usage. In light of this, this review provides an overview of different types of. This article was authored by Vineshvara S, Sudakomori ECC, Balasubramanian ES and others. We are article.tv, links in the description below.