 This study assessed the e-health literacy, pre-existing knowledge and the nursing students' perceptions and attitudes towards e-health among undergraduate nursing students. The results showed that students in Level 4 had higher scores of knowledge in the use of e-learning technology, than those in the first entry university nursing program. Additionally, the students used the internet frequently, especially to access social media and search for health and medical information for their studies. Their attitudes towards e-health and technology were also found to be positive. The study recommended that digital literacy should be enhanced in the nursing education curriculum to further strengthen the knowledge, and skills towards the use of e-health and health technology among nursing students. This article was authored by Eusebius Lekolakolomokil, Migral P. Lohan and Vlajling Mabina Mogali.