 This paper examines the sentiment of tweets about COVID-19 and Mpox, the top hashtags used in those tweets, and the top words used in those tweets. The findings show that nearly half of the tweets had a negative sentiment, while 32% had a positive sentiment and 26% had a neutral sentiment. Additionally, the top hashtags were hashtag COVID-19, hashtag coronavirus, hashtag pandemic, hashtag world health organization, hashtag who, and hashtag Ukraine. The top words were corona, virus, pandemic, world, health, and Ukraine. This paper also compared its findings with 49 prior studies in this field, showing that this paper contributes significantly to the existing body of knowledge. This article was authored by Nirmalya Fakhor.