 At Synthes we're passionate about the bioeconomy and making it better. We provided advanced tools to the bio industries that in many ways have failed to exploit the developments in computational technologies that have transformed other sectors. Those other industries have boosted their performance by integrating software with hardware and to use the community through an operating system. Bioscience had no operating system so at Synthes we created one. It's based on an open source high-level language written specifically for biologists. To be innovative you have to be unhappy with the way things are today. The more frustration the better. And then you have to have the imagination and the creativity to improve the situation. And finally you need the raw determination and resilience to make that change happen. It takes a very special team to do that. Ours is highly intelligent, creative and multidisciplinary. But also cohesive in the face of that inherent dissatisfaction that gives purpose to our ambition. If I had to sum this up in a single word I would say that we have audacity. Biology has been our greatest resource for thousands of years. We have depended upon it for food, fuel, materials and medicines. However climate change and a growing population is upon us. And by mid-century we're going to have to produce twice the amount of food with half the land and water we use today. We need to break our reliance on the oil economy. We must stay ahead of antimicrobial resistance and generally improve medical care for all. Biology holds potential solutions to all these grand challenges. But the sad fact is that biotechnology development takes too long, costs too much and fails too often. At Synthes we're reversing that trend with our operating system that links bioscience, computation and automation. This will help biologists around the globe better deal with the complexities of working with living systems, enabling us to build a bigger, stronger bioeconomy and a more sustainable future.