 Chow gas disease is a major tropical infection caused by the parasite trapanosoma cruzi. It primarily affects impoverished populations living in areas where the vector insects are present. Research into the disease has revealed its complex nature with multiple transmission routes and a variety of clinical manifestations. Despite advances in understanding, there remain significant gaps in knowledge and further research is needed to develop effective control measures. This review provides an overview of the main aspects of chow gas disease, including transmission, diagnosis, treatment and prevention. This article was authored by Jose A. de Fuentes Vicente, Nancy G. Santos Hernandez, Christian Ruiz Castillos, and others.