 This study aimed to investigate university students' attitudes towards COVID-19 vaccination in the UAE, determine factors associated with vaccine hesitancy, and understand underlying reasons. The study found that 31.8% of students demonstrated vaccine hesitancy, and that this was associated with negative beliefs and attitudes towards the vaccine, high perceived adverse effects, and not perceiving easy access to a vaccination centre. To increase COVID-19 vaccination uptake, interventions could focus on reducing fears about adverse effects and highlighting individual and societal benefits of the vaccination. This article was authored by Hamza Alzabadi, Katarina Samariniya, Basim Asadik, and others.