 Dr. Ranjan Shetty, interventional cardiologist in Manipal Hospital, Bangalore. Tavi is right now restricted to intermediate and high-risk individuals. That means it is done for elderly individuals who have some risk factors, who are high risk for surgery. As you realize, people above 70, above 80, a long with heart problem, they are likely to have lung problem, they are likely to have liver or some other problem, their mobility is likely to be restricted. Most of them do have diseases like COPD, advanced liability, uncontrolled BV, previous stroke and these kind of diseases. All these diseases make surgery for aortic stenosis high risk. These would be the candidates for Tavi, because here it is much less invasive and it is technically done like at Jopla, hence it becomes safer. So right now world over it is approved for what we call as an intermediate or high risk surgical candidates, but there are trials in western world which is now done for low risk individual. But it is unlikely to be applicable for very young individual, but it is likely to be applicable for people above 60 or 65 with one or two risk factors.