 Since the early days of Wyoming agriculture, applied research has been crucial to the success of farmers and ranchers. To help meet localized research needs, a series of research stations was developed. One such center is located near Sheridan, Wyoming. The Sheridan Research and Extension Center, as it is known today, continues to provide research-based information for agriculture in Northeast Wyoming and beyond. The Research and Extension Center was founded in 1916 on a dryland parcel of 306 acres near Wyarno, east of Sheridan. Through the years, research at the center has focused on all aspects of agriculture. Even the shelter belt, planted to protect the station from wind, doubled as a test of tree varieties suited to growing in the high plains. Today, the Sheridan Research and Extension Center is managed by the University of Wyoming as one of four agricultural experiment stations located around the state. The center has developed a closer relationship with Sheridan College over the years. Recently, the station began managing 500 acres of irrigated land owned by a local foundation, Whitney Benefits. Research today includes work on forage for Wyoming's climate, native plant extracts for cancer treatment, and great variety trials to improve Wyoming viticulture. The center typically holds a field day in early summer, but is open to the public at any time. For the University of Wyoming Extension, I'm Milton Geiger, Exploring the Nature of Wyoming.